In 1890, a German scientist named Robert Koch thought he’d invented a cure for tuberculosis, a substance derived from the infecting bacterium itself that he dubbed Tuberculin. His substance didn’t actually cure anyone, but it was eventually widely used as a diagnostic skin test. Koch’s successful failure is just one of the many colorful cases featured in Dead Ends! Flukes, Flops, and Failures that Sparked Medical Marvels, a new nonfiction illustrated children’s book by science historian Lindsey Fitzharris and her husband, cartoonist Adrian Teal.

The couple decided to collaborate on children’s books as a way to combine their respective skills. Granted, “[The market for] children’s nonfiction is very difficult,” Fitzharris told Ars. “It doesn’t sell that well in general. It’s very difficult to get publishers on board with it. It’s such a shame because I really feel that there’s a hunger for it, especially when I see the kids picking up these books and loving it. There’s also just a need for it with the decline in literacy rates. We need to get people more engaged with these topics in ways that go beyond a 30-second clip on TikTok.”

Their first foray into the market was 2023’s Plague-Busters! Medicine’s Battles with History’s Deadliest Diseases, exploring “the ickiest illnesses that have infected humans and affected civilizations through the ages”—as well as the medical breakthroughs that came about to combat those diseases. Dead Ends is something of a sequel, focusing this time on historical diagnoses, experiments, and treatments that were useless at best, frequently harmful, yet eventually led to unexpected medical breakthroughs.